L Methylfolates

Jeremy Cox
18 min readMay 12, 2024
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Welcome to our exciting roundup of the top products that feature L Methylfolate! This article will guide you through a world of innovative and effective supplements, each designed to support optimal health and wellness. As a key player in the realm of folate, L Methylfolate is a critical ingredient that has been incorporated into a range of high-quality products. Join us in exploring the possibilities as we dive into the world of L Methylfolate and its many benefits.

The Top 15 Best L Methylfolates

  1. Thorne 5-MTHF 1 mg: L Methylfolate Supplement — Experience optimal folate supplementation with pure, tissue-ready 5-MTHF in Thorne’s high-quality, science-based 1 mg 60 Capsules, trusted by thousands of health-conscious consumers.
  2. Now Foods Methyl Folate 5000 mcg — High Bioavailability L-Methylfolate Supplement — Now Foods Methyl Folate 5000 mcg — 50 Veg Capsules: Superior bioavailable 5-MTHF for optimal folate utilization, with exceptional customer satisfaction and a high 4.8 rating.
  3. L-Methylfolate Extra Strength Capsules for Daily B-Vitamin Support — Experience optimal Folate absorption with Nature’s Truth L-Methylfolate Extra Strength Capsules, offering a non-GMO, gluten-free, and high-quality supplement for an energizing start to your day.
  4. Hypoallergenic Active B-Complex with Quatrefolic L Methylfolate — Boost your daily wellness routine with Integrative Therapeutics’ Active B-Complex, featuring stabilized glucosamine salt Quatrefoil for optimal folic acid absorption and improved homocysteine levels.
  5. L Methylfolate 5-MTHF Professional Strength Capsules — Experience the ultimate power of methylation with Triquetra Health’s professional-strength L-Methylfolate 5-MTHF supplement, delivering a clinically-validated dosage of methyl folate for optimal health and wellness.
  6. Universally Metabolized Folate Capsule for Pregnancy & Wellness — Pure Encapsulations Folate 400 offers a quality, gluten-free, non-GMO source of natural Metafolin L-5-methyltetrahydrofolate, providing optimal folate support.
  7. Seeking Health L-5-MTHF 1,700 mcg DFE Folate Capsule — Experience the pure, non-racemic L-methylfolate in Seeking Health’s L-5-MTHF capsules, providing efficient methylation support and promoting overall health, while considering individual differences and side effects.
  8. Solgar Metafolin Folate 800 mcg — Effective L Methylfolate Tablets — Solgar’s Metafolin Folate 800 mcg supports maternal health and fetal development with a single prenatal B vitamin tablet, offering essential folate, crucial for reducing birth defects and promoting heart, nervous system, and DNA health.
  9. MethylPro B-Complex with L-Methylfolate — Boost Mood and Energy — Experience the power of L-Methylfolate in MethylPro — B-Complex + 10 mg L-Methylfolate — 30 Capsules, combining a full-spectrum of highly bioavailable B-vitamins and essential cofactors for optimal mood, cardio, and nerve function support.
  10. MD Life L Methylfolate 5 mg Supplement — Experience the powerful, bioactive benefits of L-Methylfolate 5 mg with our expertly formulated MD Life supplement, specifically designed to support cardiovascular health and nervous system function.
  11. The Vitamin Shoppe L-Methylfolate Prenatal Support for Women’s Health — 60 Vegetable Capsules — Support your baby’s development and your own health with The Vitamin Shoppe’s prenatal supplement, offering 800mcg of methylfolate in a vegetarian, gluten-free, nut-free capsule — designed to be easily absorbed for optimal results.
  12. Fast-Acting L-Methylfolate Supplement — Experience the power of L-Methylfolate, the metabolically active form of Folic Acid, with PipingRock’s high-potency, quick-release capsules, perfect for supporting your body’s needs.
  13. BioCoenzymated Methylfolate 60 Tablets for Enhanced Nutritional Support — Boost your health with Natural Factors BioCoenzymated Methylfolate, a once-a-day synergistic formula featuring bioactive forms of folate and vitamin B12, backed by 4.8-star rating and 829+ satisfied customers.
  14. Doctor’s Best Fully Active Folate L Methylfolate Supplement — Gluten Free — Elevate your overall wellness with Doctor’s Best Fully Active Folate 800 mcg, providing vital MTHF for healthy mood, memory, and circulation support.
  15. Efficient Methylfolate for Optimal Health and Methylation Support — Boost your folate intake with Klaire Labs L-Methylfolate 60 Capsules, a highly bioavailable, hypoallergenic supplement that efficiently supports methylation, homocysteine metabolism, and nervous system function.

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Reviews

Thorne 5-MTHF 1 mg: L Methylfolate Supplement

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Thorne’s 5-MTHF 1 mg capsules provide a rich source of tissue-ready folate, a vital B-vitamin for optimal health and well-being. These capsules are an excellent choice for individuals seeking support for methylation processes and overall health. The absence of unnecessary binders, coatings, disintegrants, fillers, or lubricants ensure optimal absorption and potency.

Thorne, a reputable brand trusted by both healthcare practitioners and consumers, delivers high-quality products with a dedication to exceptional formulation and strict adherence to current Good Manufacturing Practices (cGMPs). The 60-capsule bottle guarantees a sufficient duration for continuous use, making this supplement a convenient addition to any daily health regimen.

Now Foods Methyl Folate 5000 mcg — High Bioavailability L-Methylfolate Supplement

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I recently tried Now Foods Methyl Folate to support my neuro health, and I must say, it’s been nothing short of impressive. As I learned I’m heterozygous for MTHFR c677t, I was hoping this supplement would alleviate some of my symptoms, and it did not disappoint!

From day one, I noticed a significant improvement in my brain fog, which has made an enormous difference in my daily life. Now, after using it for a few weeks, I’m seeing additional benefits to my overall health. The only side effects I’ve experienced are slightly greenish poo and a slightly smaller bank account — but those are minor trade-offs given the improvements I’m experiencing.

I was initially reluctant due to the plastic bottle, as I prefer glass containers, but I’ve grown to appreciate this product enough to continue buying it. Plus, the capsules can be easily opened if you need a lower dosage — a feature I didn’t expect but am glad to have.

All in all, I wholeheartedly recommend Now Foods Methyl Folate to anyone who wants to support their neurological health. It might just change your life, as it did for me!

L-Methylfolate Extra Strength Capsules for Daily B-Vitamin Support

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Nature’s Truth L-Methylfolate capsules offer an extra strength source of this essential B-Vitamin, L-Methylfolate. As a water-soluble vitamin, it readily enters your system, ready to help support your body’s needs.

Designed to be easy to swallow, these capsules are non-GMO, gluten-free, and contain no wheat, yeast, milk, lactose, or soy. You’ll also appreciate that Nature’s Truth L-Methylfolate capsules are made without any artificial colors, flavors, sweeteners, or preservatives, ensuring the purity you expect from a high-quality supplement.

Hypoallergenic Active B-Complex with Quatrefolic L Methylfolate

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Active B-Complex by Integrative Therapeutics is a daily supplement that provides essential vitamins B1, B2, B6, B12, and folate, all in their active and bioavailable forms. This formula is designed to help support overall health and well-being, as well as enhance energy production and red blood cell formation. The addition of Quatrefoli provides a stabilized form of folic acid, which is crucial for methylation processes in the body.

The supplement is free from common allergens, such as soy, dairy, gluten, salt, and preservatives, making it suitable for individuals with sensitive systems. With a serving size of two capsules, the bottle offers a 30-day supply for optimal health maintenance.

Users of Active B-Complex have reported a variety of benefits, including increased energy levels, improved mood, and reduced fatigue. Some customers have also highlighted the supplement’s ability to effectively address methylation issues due to genetic mutations. However, a small number of reviews have reported unpleasant side effects, such as heartburn and skin irritation.

Overall, Active B-Complex by Integrative Therapeutics appears to be a high-quality supplement, formulated with active and bioavailable vitamins for optimal absorption and health benefits. It may be particularly beneficial for individuals with allergies or those who require support for their methylation processes.

L Methylfolate 5-MTHF Professional Strength Capsules

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Trifecta is an impressive supplement that offers a professional strength, providing 15mg of L-Methylfolate in a 5-MTHF calcium salt form. This is the most active form of folate, making it ideal for individuals looking to bolster their methylation processes. One of the best features of this supplement is the synergy it creates with methylcobalamin B12, another vital component in the body’s methylation process. Without the presence of methylcobalamin B12 in the body, the methylation process cannot be completed, and homocysteine cannot be broken down efficiently.

The supplement is available in capsule form, offering 60 capsules for users to enjoy. The high-quality formula and affordable pricing make it an excellent option for those seeking optimal supplementation. The airtight, amber glass bottle provides additional peace of mind, as it effectively shields the supplement from natural exposure to sunlight and oxygen, ensuring optimal efficacy. With 15mg of active folate and only one capsule per serving, this supplement is a reliable and effective pick for those looking for a reasonable and capable solution for their health needs.

Universally Metabolized Folate Capsule for Pregnancy & Wellness

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Pure Encapsulations Folate 400 is a popular supplement that offers a high-quality, naturally occurring form of folate. This supplement provides 400 mcg per capsule of Metafolin L-5-methyltetrahydrofolate (L-5-MTHF), which is easily absorbed by the body.

It is suitable for those with gluten and non-GMO dietary restrictions. The recommended usage is 1 capsule, 1–2 times daily, with meals. However, it is essential to consult with a healthcare professional before using this product, especially if pregnant or lactating, taking medications, or have a health condition.

The product should be stored in a cool, dry place with a safety seal intact.

Seeking Health L-5-MTHF 1,700 mcg DFE Folate Capsule

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L-5-MTHF Capsules by Seeking Health offer a convenient, easy-to-absorb supplement for supporting healthy methylation processes. The pure non-racemic L-methylfolate, an active coenzyme form of folate, can be especially beneficial for those with absorption or metabolic defects.

The capsules efficiently support DNA biosynthesis, homocysteine metabolism, and nervous system function, with the predominant folate in circulation and the only form of folate that can cross the blood-brain barrier. Users report noticeable improvements in their health and well-being, especially with proper dose customization. Be sure to consult your healthcare professional for testing and dosage recommendations.

Solgar Metafolin Folate 800 mcg — Effective L Methylfolate Tablets

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For years, I’ve been using Solgar Metafolin Folate tablets during pregnancy to support my overall health and my baby’s development. These tablets are designed to provide essential folate, a crucial nutrient that expectant mothers should consume to avoid potential birth defects.

One of the features that stand out to me is the size of the tablet. I find it easy to swallow and incorporate it into my daily routine, ensuring that I get the necessary daily dose of folate. Moreover, Solgar ensures that their products are of high quality, and the vegetarian capsule allows me to maintain my dietary preferences.

However, I’ve noticed that taking more than the recommended dosage doesn’t necessarily yield better results. In fact, it may lead to unwanted consequences. So, it’s essential to follow the suggested use guidelines for optimal benefits.

While I’ve experienced positive effects during my pregnancy, individual results may vary. However, Solgar has always seemed to prioritize purity and excellence in their products, and the supplement has been a reliable and convenient choice for me. Overall, I recommend Solgar Metafolin Folate tablets for any pregnant woman seeking to support her maternal health through a comprehensive prenatal vitamin.

MethylPro B-Complex with L-Methylfolate — Boost Mood and Energy

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MethylPro offers a unique blend of L-Methylfolate and a full spectrum of highly bioavailable B vitamins, making it a fantastic choice for those looking to support their mood, energy, and overall well-being. The supplement is an excellent option for individuals who have difficulty absorbing folic acid, as it is specifically formulated for those with the homozygous C677T MTHFR gene. MethylPro also stands out for its top-notch customer service and commitment to providing quality supplements.

MD Life L Methylfolate 5 mg Supplement

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I recently started taking MD Life L Methylfolate 5 mg daily, and I must say, it’s been a game-changer for my overall well-being. Being a vegetarian, I knew I needed an excellent source of folate for my health. When I first tried it, the capsules were easy to take and didn’t cause any digestive issues.

One of the key highlights that stand out for me is the product’s ability to increase blood serum folate levels much more effectively than traditional folic acid supplements. This has been a game-changer in my life, as I’ve noticed improvements in my mood and cognitive function.

Although I don’t have any specific complaints about this product, I wish the supplement came in smaller capsule sizes. As someone with a sensitive stomach, a smaller, more discrete option would be ideal.

Overall, I’m very satisfied with the benefits I’ve experienced from using MD Life L Methylfolate 5 mg daily. The difference is noticeable, and I highly recommend it if you’re in the market for an effective folate supplement.

The Vitamin Shoppe L-Methylfolate Prenatal Support for Women’s Health — 60 Vegetable Capsules

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Methylfolate, a powerful supplement from The Vitamin Shoppe, is designed to support women’s health, particularly during pregnancy and baby development. This highly absorbable form of folate has been praised for its ability to improve cardiovascular and brain health, as well as support cell division for the creation of DNA and other genetic material.

Suitable for vegetarians, this prenatal supplement is free from gluten, dairy, soy, and nuts, making it an ideal choice for expecting wellness seekers. The dosage, one vegetable capsule per day, is recommended to be taken with a meal for maximum effectiveness.

Fast-Acting L-Methylfolate Supplement

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L-Methylfolate is the biologically active form of Folic Acid, providing a unique B supplement that can effectively support your body’s needs. It saves your body the trouble of converting Folic Acid into 5-Methyltetrahydrofolate (5-MTHF), making it more efficient. This essential B vitamin is ideal for addressing Folate Deficiency and is commonly included in multivitamin supplements.

PipingRock offers high-quality L-Methylfolate (Extra Strength) in a convenient, non-GMO, gluten-free formula. PipingRock’s L-Methylfolate comes in quick-release capsules, delivering 7.5 mg of this beneficial ingredient per serving. The company takes pride in offering an ever-growing selection of products to help you achieve your wellness goals.

BioCoenzymated Methylfolate 60 Tablets for Enhanced Nutritional Support

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Experience the power of Natural Factors BioCoenzymated Methylfolate 60 Tablets, a game-changer in the world of nutritional supplements. This unique formula is backed by emerging research and provides a one-a-day dosage of key B vitamins designed to support your body’s functions, such as cell division, DNA synthesis, and neurotransmitter production. The star ingredient here is 5-MTHF coenzymated folate, which ensures a higher absorption rate and can effectively increase blood folate levels, benefiting those with genetic variations that impair the metabolism of standard B vitamins.

Another advantage of BioCoenzymated Methylfolate is its use of methylfolate, making it easier for the body to absorb and utilize than regular folic acid. The dosage of 1,000 mcg per tablet is ideal for many individuals, offering flexibility in terms of adjusting supplement intake based on specific health needs. As a quick-melt tablet, this supplement is perfect for those who have difficulties swallowing pills or require a hassle-free solution.

Furthermore, Natural Factors BioCoenzymated Methylfolate boasts a commitment to quality and high-quality ingredients. The product is gluten-free, non-GMO, suitable for vegetarians, and is conveniently sublingual, making it a popular choice for those who want the most bioavailable and advantageous forms of these two vital nutrients.

A potential drawback of this supplement is individual responses may vary, and it’s always essential to consult a healthcare professional before starting any new supplement regimen, especially if you have pre-existing health conditions or are on medication.

Doctor’s Best Fully Active Folate L Methylfolate Supplement — Gluten Free

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Doctor’s Best Fully Active Folate with Quatrefolic is an impressive folate supplement that boasts bioactive availability, potent formulation, and a lack of side effects. Suitable for those with specific dietary requirements or health concerns necessitating higher folate intake, this supplement provides an adequate 800 micrograms of fully active folate. The supplement’s absence of fillers and binders, along with its thoughtful packaging and careful dosage, adds to the overall positive experience.

With a fast-acting nature that leaves users feeling well and energized, this folate supplement is highly recommended for those seeking a high-quality, bioactive, and potent source of folate.

Efficient Methylfolate for Optimal Health and Methylation Support

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As someone who understands the importance of a well-rounded folate intake, I decided to give Klaire Labs L-Methylfolate a try. This supplement is tailored to individuals who may not absorb conventional folic acid as efficiently, making it a more bioavailable option for a variety of people.

One of the things that stood out about this product is its 1,700 mcg DFE (1000 mcg) folate content per capsule, which supports numerous bodily functions, including methylation, DNA biosynthesis, and nervous system function. The capsules are easy to swallow and have helped me maintain a healthy folate intake.

However, I did encounter one minor issue: the lack of a receipt in the packaging. Despite this minor inconvenience, I would still recommend Klaire Labs L-Methylfolate to those looking for a high-quality supplement that can efficiently support overall health and energy levels.

The Klaire Labs L-Methylfolate effectively provides an alternative for individuals at risk of folate deficiency and is a convenient addition to anyone’s daily supplement regimen. It may also be beneficial for women, children, and those with absorption or metabolic challenges. With its 4.8-star rating from satisfied customers and a reputation for being hypoallergenic, this product truly seems worth a try.

Buyer’s Guide

L Methylfolate, also known as 5-Methyltetrahydrofolate, is a naturally occurring form of folate that is essential for maintaining good health. It plays a crucial role in brain function, cell growth, and DNA synthesis. This buyer’s guide will provide important information about L Methylfolate, its features, considerations, and general advice to help you make an informed decision when choosing a supplement.

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Understanding Folate and Its Importance

Folate, also known as vitamin B9, is a vital nutrient that supports various body functions. It contributes to the production of DNA and RNA, helps prevent birth defects, and aids in cell growth and division. Lack of folate in the body can lead to anemia, poor brain development during pregnancy, and certain cancers. However, not all people can easily absorb and utilize folate from food.

The Role of L Methylfolate

L Methylfolate is a form of folate that is easily absorbed and utilized by the body. It is also known as 5-Methyltetrahydrofolate, which is the active, bioavailable form of folate that is found in food. L Methylfolate plays a critical role in brain health, mood regulation, and DNA synthesis. It is particularly beneficial for individuals who have difficulty converting inactive folic acid to its active form in the body due to genetic mutations or certain health conditions.

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Choosing the Right L Methylfolate Supplement

When selecting an L Methylfolate supplement, consider the following factors: dosage, quality, and any additional ingredients. Look for supplements that contain at least 1,000 mcg of L Methylfolate per serving, which is typically the recommended amount for adults. Choose a high-quality supplement made from natural, non-synthetic sources. Additionally, avoid supplements that contain synthetic folic acid and instead opt for those that utilize L Methylfolate.

Cautions and Concerns

While L Methylfolate is generally well-tolerated, it’s essential to consult with your healthcare provider before using any supplements, especially if you have a medical condition, are pregnant, or are breastfeeding. Additionally, be aware that L Methylfolate supplements should not be used as a substitute for a healthy, balanced diet. Incorporate a variety of folate-rich foods, such as leafy greens, citrus fruits, and legumes, alongside supplementation to ensure optimal health and wellbeing.

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FAQ

What is L Methylfolate?

L Methylfolate, also known as 5-methyltetrahydrofolate, is an active form of folic acid. It is a naturally occurring compound in the human body and is essential for various biological processes, including the formation of new cells, the synthesis of DNA, and the prevention of certain birth defects. L Methylfolate is particularly important for expectant mothers, as it helps prevent neural tube defects in their offspring.

L Methylfolate supplements are available in different forms and dosages, making it a popular choice for individuals looking to increase their folate intake. These supplements are available in capsules, tablets, or liquid form, and they come in different strengths to cater to individuals with varying needs.

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How does L Methylfolate work?

L Methylfolate works by providing the body with an easily absorbed form of folic acid, which is essential for the synthesis of DNA and the formation of new cells. It works as a coenzyme, participating in various reactions within the body, including the conversion of homocysteine to methionine. This process is crucial for the proper functioning of numerous biological pathways, such as those involved in DNA synthesis and the regulation of gene expression.

L Methylfolate also plays a critical role in the production of energy within the body, as it is involved in the methylation cycle. This cycle is responsible for the transfer of a methyl group from one molecule to another, which is essential for various biochemical reactions, including cellular metabolism, neurotransmitter synthesis, and the regulation of gene expression.

What are the benefits of L Methylfolate?

The benefits of L Methylfolate are numerous, especially for individuals who have difficulty absorbing folic acid or require additional support in maintaining optimal folate levels. Some of the key advantages include the following: * Improved DNA synthesis and cell growth: L Methylfolate is essential for the proper functioning of cellular processes, including DNA synthesis and the formation of new cells. It helps maintain healthy cellular growth and development.

* Prevention of birth defects: L Methylfolate is particularly important for expectant mothers, as it helps prevent neural tube defects in their offspring. Folic acid supplementation, including L Methylfolate, is recommended for all women planning to become pregnant, as it can significantly reduce the risk of neural tube defects in the baby.

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Who should consider taking L Methylfolate supplements?

Individuals who may benefit from taking L Methylfolate supplements include those who are pregnant, planning to become pregnant, or at risk of developing neural tube defects. Others who might consider supplementation include older adults, individuals with malabsorption issues (such as celiac disease), and those who consume alcohol excessively.

Additionally, L Methylfolate supplements can also be beneficial for individuals with elevated homocysteine levels, which may be associated with an increased risk of cardiovascular disease, cognitive decline, and other health concerns. Consulting with a healthcare professional before starting any supplement is always recommended.

How should L Methylfolate supplements be taken?

L Methylfolate supplements should be taken as directed by a healthcare professional or according to the package label. They are available in different forms, such as capsules, tablets, or liquid, and they can be taken with or without food. It is essential to follow the recommended dosage and to consult with a healthcare professional before starting any supplement, especially for pregnant women or those at risk of developing neural tube defects.

It is also important to note that excessive amounts of L Methylfolate or other folate-related supplements are not advisable, as they can be associated with certain health risks, such as masking vitamin B12 deficiency or increasing the risk of heart disease. Maintaining a balanced diet and ensuring that you have adequate folate levels is crucial for overall health.

Are there any potential side effects of L Methylfolate supplements?

Common side effects associated with L Methylfolate supplements are generally mild and may include gastrointestinal disturbances, such as nausea, diarrhea, or upset stomach. However, these side effects are usually transient and do not persist in most individuals. In rare cases, more severe side effects may occur, but these are generally related to overdosage or taking L Methylfolate in combination with other medications or supplements.

It is essential to consult with a healthcare professional before starting any supplement, especially if you are pregnant, have a medical condition, or are taking medications that may interact with L Methylfolate. In conclusion, while L Methylfolate supplements offer numerous benefits for individuals looking to increase their folate intake, it is crucial to follow the recommended dosage and to consult with a healthcare professional before starting any supplement.

As an Amazon Affiliate, I may earn through qualifying purchases.

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